Formulation And Development – Full Time Freshers

Key Responsibilities

1. Pre-formulation Studies

• ✓ Characterization: Testing the raw API for physical and chemical properties like solubility, pH stability, and melting point.
• ✓ Compatibility: Conducting studies to see if the drug reacts negatively with certain excipients or packaging materials.

2. Product Design & Optimization

• ✓ Recipe Creation: Designing different versions of a drug (prototypes) to find the one with the best stability and bioavailability.
• ✓ DoE (Design of Experiments): Using statistical software to systematically test different ingredient ratios to find the Goldilocks formula.

3. Stability & Quality Testing

• ✓ Shelf-Life Testing: Placing batches in Stability Chambers to see how they react to extreme heat, humidity, and light over time.
• ✓ Dissolution Profile: Testing how quickly a tablet dissolves in a simulated stomach environment to ensure the drug is released correctly.

4. Scale-Up & Technology Transfer

• ✓ Lab to Factory: Moving a formula that worked in a small beaker to large-scale machines that produce millions of tablets.
• ✓ Troubleshooting: Solving real-world manufacturing issues like tablets sticking to the machine or capsules becoming brittle.